URINE EXAMINATIONS (PHYICAL AND MICROSCOPIC)
urine examination
physical or visual
* Colour
Normal - pale yellow
Abnormal- yellow, brown, red-brown and red
Color less - significantly diluted urine
Appearance and color
Cloudy- The presence of phosphate, carbonate, urates, uric acid, leukocytes, bacteria, yeast, spermatozoa, prosthetic fluid, mucin mucus threads, clumps, pus, tissue facial contamination, and radiographic dye
Milky- The presence of fat (lipiduria, opalescent chyluria), milky emulsified paraffin
Yellow- Acriflavin
Yellow-orange- Concentrated urine, urobilin, bilirubin
Yellow-green - bilirubin - biliverdin
Red- Hemoglobin, erythrocytes, myoglobin, porphyrin, fusion, aniline dye, beets
Normal - normal urine is pale yellow to amber in color and is clear
Turbid
- #
- Markers of urine examinations
- Cancer
- Small cancerous tumors that have just started growing have small, delicate blood vessels that are prone to burst easily. This is why hematuria is a common early symptom of bladder cancer.
- kidney stone
Crystals in urine, also known as crystalluria, can occur for various reasons. Let’s explore the causes and implications:
Dehydration: Not drinking enough water can lead to concentrated urine, which increases the likelihood of crystals forming. Proper water intake is essential to prevent this.
Diet: Consuming large amounts of certain foods, such as protein, salt, and fruits and vegetables, can contribute to crystal formation in urine. Additionally, a protein-rich diet may elevate uric acid levels, leading to crystals.
Medications: Some medications, including amoxicillin, acyclovir, sulfonamides, atazanavir, and methotrexate, can cause crystals in urine.
Underlying Conditions:
- Kidney Stones: Crystals can aggregate and form kidney stones, which can obstruct urine flow and cause pain.
- Urinary Tract Infections (UTIs): Infections can alter urine composition and promote crystal formation.
- Rare Inherited Disorders: Crystals like cystine and xanthine are associated with specific genetic conditions.
- Urinary tract infection (UTI)
urinary tract infection (UTI) is an infection that can occur in any part of the urinary system, which includes the kidneys, ureters, bladder, and urethra. Most UTIs involve the lower urinary tract, affecting the bladder and urethra. Women are more susceptible to UTIs than men.
Common symptoms of a UTI include:
- Pain or discomfort during urination
- Frequent urination
- Urgency to urinate
- Cloudy or bloody urine
- Foul-smelling urine
- Low-grade fever
If you suspect a UTI, it’s crucial to seek medical attention. Left untreated, UTIs can lead to more severe complications. Treatment typically involves antibiotics to clear the infection. Remember to stay hydrated and maintain good hygiene to prevent UTI in future
- Enlarged prostate (men only)
- Certain diseases (like sickle cell anemia and cystic kidney disease)
- Injury to the kidneys
*Specific gravity
Specific gravity means the number of ions percent in the urine in its normal range of 1.020. Normally it depends on the urine concentrations and pH. In high concentrations the specific gravity is low and ph is also low and vice versa
Principle of specific gravity determinations
The test detects the ion concentration of the urine. Using the reagent bromothymol blue notice the color change from blue-green to yellow
chemical properties of urine
*pH
The test paper contains indicators of methyl red and phenolphthalein. its color change we can detect the pH level
Normal range 6.5 to 7.5
the substance containing the urine depends the pH range
*Protein
*Glucose
*Ketone
*Urobilinogen
*Bilirubin
*Blood
*Nitrite
microscopic
*RBC
*WBC OR Pus cells
*Epithelial cells
*Cast
*Crystal
*Bacteria
lack of water taking, or any other reasons, can make chance of bacterial growth is high. in most of the case if bacteria is present nitrate also present
*Other findings
Visual, chemical, and microscopic tests are the major checkpoints of complete urinalysis. Urinalysis is frequently used to screen for urinary tract infections (UTIs), kidney and liver issues, and diabetes. But urine is the major marker of the body anything that happens inside of the body majority we can detect using urine analysis.
For microscopic findings of urine
Puscells
normally we use high-power feed( microscope ) so that time is normal urine we can see 2 to 3 pus cells (WBC) or less but in some abnormal conditions, we can see more pus cells. For example in urinary tract infections, the presence of bacteria can be found>50 or 100, depending on the patient's physical conditions and affected organisms. Sometimes conditions like gonococci(sexually transmitted disease) the pus cells become numerous
blood cells or RBCs in the urine
Blood in the urine means there are red blood cells (RBCs) in the urine. Often, the urine looks normal to the naked eye. But when checked under a microscope, it contains a high number of red blood cells. In some cases, the urine is pink, red, or the color of tea, which you can see without a microscope.
causes
Most of the causes of blood in the urine are not serious. For example, heavy exercise may cause blood in the urine, which often goes away daily.
Other, more serious causes include:
Some medications cause blood in the urine. And many people have it without having any other related problems.
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